Fundamentals: Table of Contents

Part 1. The Basics
Cardiac Cycle
Time Varying Elastance
Preload
Afterload
Contractility
Lusitropy
Frank-Starling Relations

Part 2: Introduction to Cardiac Pathology
Aortic Stenosis
Aortic Insufficiency
Mitral Stenosis
Mitral Insufficiency
Coronary Circulation
Heart Failure with Reduced EF (HFrEF)
Heart Failure with Preserved EF (HFpEF)
Cardiogenic Shock (CGS)
Pericardial Physiology

Part 3: Introduction to Oxygen Delivery and the ABG
Oxygen
The 5 causes of Hypoxemia
Carbon Dioxide
The ABG
Oxygen Delivery Tutorial

ECMO/MCS: Table of Contents

Quick Review of KEY aspects of Cardiac Function
Quick review of the PV Loop: Preload, Afterload, Contractility

Quick Review of Gas Exchange and O2 Delivery
Oxygen
The 5 causes of Hypoxemia
Carbon Dioxide
The ABG
Oxygen Delivery Tutorial

VV ECMO - The Basics
Basic V-V ECMO Physiology
ECMO Device Hemodynamics
Recirculation

VA ECMO and Acute MCS
Basic V-A ECMO Physiology, Harlequin Syndrome
Ventricular afterload and VA ECMO
IABP and VA ECMO
Direct LV decompression (vent and transvalvular pump)
RV Function and PAHTN: ECMO, RVAD, ASD

Advanced: Table of Contents

Basic Concepts from Cells to Chambers
Introduction
Anatomy
The Circulatory Loop
Cardiac Muscle Physiology
Organ Level Physiology

Basic Physiology with the PV LOOP (Lessons and Tutorials)
The Cardiac Cycle and Pressure-Volume Loops
Pressure-Volume Relations
Preload
Afterload
Contractility
Lusitropy
Starling Curves
Ventricular-Vascular Interactions
Right Ventricular Mechanics
Atrial Mechanics
The Pericardium and Ventricular Interactions
Normal Valve Function and Flow Patterns

Advanced Concepts from Cells to Chambers and Control Mechanisms
Excitation-Contraction Coupling
Determinants of Myocardial Oxygen Consumption
Basics of Myocardial Metabolism
Regulation of Coronary Blood Flow
Autonomic Control of the Circulation
Basics of Cardiovascular Receptor Biology and Pharmacology
Exercise Physiology

Appendix
Invasive Assessment of Pressure-Volume Relations
Noninvasive Estimation of Pressure-Volume Relations