Thank you! I can reproduce some helpful variations with respiration, and the AV dissociation trick with V pacing works perfectly.

I’m trying to simulate greater variations in intrathoracic pressure during respiration, to demonstrate clear changes on transvalvular mitral flow and AO pulse pressure, but even at Tidal Volume maxed to 1000cc, the pressure variation is relatively small. How might I increase the amplitude of the change? Is there an airway resistance parameter I can change? Thanks again. Terry