Student

An introduction to the key concepts. For students of all levels
Harvi-Student: Table of Contents

Part 1. The Basics
Cardiac Cycle
Time Varying Elastance
Preload
Afterload
Contractility
Lusitropy
Frank-Starling Relations

Part 2: Introduction to Cardiac Pathology
Aortic Stenosis
Aortic Insufficiency
Mitral Stenosis
Mitral Insufficiency
Coronary Circulation
Heart Failure with Reduced EF (HFrEF)
Heart Failure with Preserved EF (HFpEF)
Cardiogenic Shock (CGS)
Pericardial Physiology

Part 3: Introduction to Oxygen Delivery and the ABG
Oxygen
The 5 causes of Hypoxemia
Carbon Dioxide
The ABG
Oxygen Delivery Tutorial

Harvi-Student: Academy

Part I: Basics of Pressure-Volume Analysis
Chapter 1: The Cardiac Cycle
Chapter 2: Pressure-Volume Relations
Chapter 3: Preload
Chapter 4: Afterload
Chapter 5: Contractility
Chapter 6: Lusitropy
Chapter 7: Frank-Starling Relations

Part II: Introduction to Cardiac Pathology
Chapter 1: Valve Diseases
Chapter 2: Coronary Circulation
Chapter 3: Heart Failure
Chapter 4: Pericardial Physiology

Part III: Oxygen Delivery and the ABG
Chapter 1: Oxygen in Lungs: Alveolar Gas Equation
Chapter 2: Oxygen in Blood: O2-Hb dissociation curve
Chapter 3: Oxygen in Blood: O2 content
Chapter 4: Aa gradient: Diffusion Abnormality
Chapter 5: Aa gradient: Shunt
Chapter 6: Aa gradient: VQ mismatch
Chapter 7: Ventilation and CO2
Chapter 8: Intro to the ABG
Chapter 9: Fick Equation
Chapter 10: Oxygen Delivery and SVO2

Harvi-Student: Simulator

Basic Cardiovascular simulation

Basic Pathophysiology

Ability to save conditions you create​​

Advanced

For a deeper dive. Especially for trainees in cardiology
Harvi-Advanced: Table of Contents

Basic Concepts from Cells to Chambers
Introduction
Anatomy
The Circulatory Loop
Cardiac Muscle Physiology
Organ Level Physiology

Basic Physiology with the PV LOOP (Lessons and Tutorials)
The Cardiac Cycle and Pressure-Volume Loops
Pressure-Volume Relations
Preload
Afterload
Contractility
Lusitropy
Starling Curves
Ventricular-Vascular Interactions
Right Ventricular Mechanics
Atrial Mechanics
The Pericardium and Ventricular Interactions
Normal Valve Function and Flow Patterns

Advanced Concepts from Cells to Chambers and Control Mechanisms
Excitation-Contraction Coupling
Determinants of Myocardial Oxygen Consumption
Basics of Myocardial Metabolism
Regulation of Coronary Blood Flow
Autonomic Control of the Circulation
Basics of Cardiovascular Receptor Biology and Pharmacology
Exercise Physiology

Appendix
Invasive Assessment of Pressure-Volume Relations
Noninvasive Estimation of Pressure-Volume Relations

Harvi-Advanced: Academy

Part I: Basics of Pressure-Volume Analysis
Chapter 1: The Cardiac Cycle
Chapter 2: Pressure-Volume Relations
Chapter 3: Preload
Chapter 4: Afterload
Chapter 5: Contractility
Chapter 6: Lusitropy
Chapter 7: Frank-Starling Relations

Part II: Introduction to Cardiac Pathology
Chapter 1: Valve Diseases
Chapter 2: Coronary Circulation
Chapter 3: Heart Failure
Chapter 4: Pericardial Physiology

Harvi-Advanced: Simulator

Advanced cardiovascular simulation with ability to simulate all forms of heart failure, valve diseases, coronary artery disease, understand myocardial energetics and introduce and vary settings of a variety of mechanical support devices and basic set of intravenous pharmacologic agents

Extensive Try-It-Now libraries

The Patient Simulator​

Ability to save, recall and share parameter sets​

ECMO

Essential physiology for all practitioners involved in ECMO and MCS
Harvi-ECMO: Table of Contents

Quick Review of KEY aspects of Cardiac Function
Quick review of the PV Loop: Preload, Afterload, Contractility

Quick Review of Gas Exchange and O2 Delivery
Oxygen
The 5 causes of Hypoxemia
Carbon Dioxide
The ABG
Oxygen Delivery Tutorial

VV ECMO - The Basics
Basic V-V ECMO Physiology
ECMO Device Hemodynamics
Recirculation

VA ECMO and Acute MCS
Basic V-A ECMO Physiology, Harlequin Syndrome
Ventricular afterload and VA ECMO
IABP and VA ECMO
Direct LV decompression (vent and transvalvular pump)
RV Function and PAHTN: ECMO, RVAD, ASD

Harvi-ECMO: Academy

Part III: Oxygen Delivery and the ABG
Chapter 1: Oxygen in Lungs: Alveolar Gas Equation
Chapter 2: Oxygen in Blood: O2-Hb dissociation curve
Chapter 3: Oxygen in Blood: O2 content
Chapter 4: Aa gradient: Diffusion Abnormality
Chapter 5: Aa gradient: Shunt
Chapter 6: Aa gradient: VQ mismatch
Chapter 7: Ventilation and CO2
Chapter 8: Intro to the ABG
Chapter 9: Fick Equation
Chapter 10: Oxygen Delivery and SVO2

Physiology of ECMO
Membrane Lung Dysfunction Lecture
LV distension on ECMO
Cardiovascular Pharmacology
Surgical Approaches to PA HTN

Harvi-ECMO: Simulator

Ability to vary a host of device and patient pulmonary and metabolic parameters with outputs that include regional blood gasses​

A more advanced library of modeled conditions specific to lung failure and acute heart failure​

Multiple cannulation configurations (VV, VA, VAV)​

Ability to add other devices (trans-valvular pumps, IABP, LV vent)​

Complete

A compilation of all the licenses
Harvi-Complete: Table of Contents

ALL BOOKS

Harvi-Complete: Academy

ALL LESSONS

Harvi-Complete: Simulator

FULL SIMULATOR

Professor

Includes all Harvi books, lessons, and simulator input/output/graphing. Additional features are listed below.
Harvi-Professor: Additional functions

Able to download 42 time-domain signals (5 ms resolution) in csv format to export to excel or graphing programs

Allows real time graphics on two different screens; second screen only displays graphics for use in teaching sessions

Harvi-Professor: Additional resources

Zoom orientation sessions to help get up and running and direct email support

Harvi-Professor: Site License Option

A Harvi Site License provides unlimited University-wide access to Harvi through the institution’s single sign on (SSO) system.

This allows all faculty and students to access Harvi through a unique URL (e.g., universityname.harvi.online) with their University username and password.

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